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Also, in 2002, a heme qinghaosu named hemart was reported and showed that hemart stalls all mechanisms of heme polymerization, which results in the death of the malarial parasite304 However, their hemart was synthesized just by mixing equivalent heme and qinghaosu in dimethyl acetamide (DMA) at 37 C for 24 hours It is not clear that hermart is a complex or a covalent adduct The primary C-centered free radical 162 is only formed by reaction of qinghaosu and heme in the presence of reducing agents, but not in the absence of the reductants In 2003, Haynes et al pointed out that qinghaosu antimalarials do not inhibit hemozoin formation and hence ruled out the role of the qinghaosu heme adduct as an inhibitor305.



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of the bond decreases. Also, the risk-neutral drift rate of the bond is equal to the short rate r(t) since the bond is a traded asset. In the Vasicek model, the bond price process is lognormal. We can also derive the process for the T-maturity instantaneous forward rate using Ito s lemma: df (r , t , T ) = d(r + e a (r r ) and the result is: df(r, t, T) = f (t, T)dt + f (t, T)dz(t) where the instantaneous volatility and drift rate of the forward rate are: f (t, T) = e a(T t) and f (t , T ) = 2 a(T t ) e (1 e a(T t ) ) a (10.55) (10.54) 2 2a2 (1 e a )2 )

Count of blocks on the device: 57606144 Number of blocks consumed by mkreiserfs formatting process: 9969 Blocksize: 4096 Hash function used to sort names: r5 Journal Size 8193 blocks (first block 18) Journal Max transaction length 1024 inode generation number: 0

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Equating corresponding terms, we obtain 1 r02 x02 y02 k1 N 2 1 1 rc k2 r01 k1 Nx01 xc 1 r02 r01 rc k2 k1 Ny01 yc 1 r02 r01 rc k2 16:2-56 16:2-57 16:2-58

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As discussed in Section 4.2, only part of the full energy available from the wind can be extracted for energy generation, quanti ed by the power coef cient, Cp . The power coef cient is the relationship of the power extraction possible to the total amount of power contained in the wind [3,8 12]. Figure 4.8 relates the power coef cient to the tip speed ratio, l, de ned as the relationship between the rotor blade tip speed and the free speed of the wind for several wind power turbines. As stated earlier, in quantitative terms, the tip speed ratio is de ned as l v/V oR/V, where o is the angular speed of the turbine shaft, v the blade tangent tip speed, and R the length of each blade. It emphasizes the importance of knowing the purpose for which the energy will be used, to allow determination of the best selection for wind power extraction. From equation (4.5), the turbine mechanical power can be given by Pt Cp rAV 3 2 kg m=s 4:13

that are awarded are always practice-altering and practice-shaping The nonnegotiable goal is to nd an implementable solution to a (previously unsolved) practical problem In other words, those people are 100 percent hands-on They may make theory, but it s the type of theory that unveils laws and principles that rmly hold in practice The type of theory that is not only enthusiastically welcomed in practice, but whose unassailably natural ultimate destination is practice, as has been for ages That is, a theory that invariably works Not so with the other, rather odd sixth discipline Those who belong to it are not the ones practicing what s under study They are not, by any stretch, the practitioners of that area Other people are doing it in the real world Their discoveries are empiricism-challenged, and the dictums are rewarded without regard for practical validity, simply on account of the analytical techniques employed.

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We will actively trade in shares of stock and the MMA by rebalancing our portfolio every in nitesimal time increment dt by changing both t and Nt at every instant in time. We will keep our short option position unchanged all the way to maturity T. At some intermediate time t (t is our running time parameter), our portfolio is worth: t = tSt Nt At ft (1.41)

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