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Another interesting property of HA pharmacology relates to a broad range of protective actions. It has been studied that HA could protect neuronal cells against nerve gas poisoning,60 against glutamate toxicity,61 against Ab toxicity,62 65 and against neuronal cells apoptosis induced by hypoxic-ischemic (HI) or oxidative stress.66 68 4.4.3.1 Nerve Gas Poisoning HA has been tested as a prophylactic drug against soman and other nerve gas poisoning with an excellent outcome.69 It works by protecting cortical AChE from soman inhibition and by preventing subsequent seizures. This prophylactic use makes HA a potential protective agent against chemical weapons. It has been demonstrated that rats can be protected against low doses of soman with pretreatment with only HA, and without typical cholinergic side effects.69 This protection was con rmed in a study with primates, where HA was compared with pyridostigmine: The cumulative dose of soman needed to produce convulsions and epileptic activity was 1.55-fold higher in the animals who received HA compared with the group of primates pretreated with pyridostigmine.60 The same study demonstrated that HA selectively inhibited red cell AChE activity, whereas pyridostigmine also inhibited plasma BuChE. Thus, the superior protection offered by HA appears to be related both to the selectivity of HA for red cell AChE, preserving the scavenger capacity of plasma BuChEs for organophosphate (OP) agents, and to the protection conferred on cerebral AChE.60 4.4.3.2 Glutamate Toxicity HA also protects primary neuronal cell culture and animals from glutamate toxicity. Glutamate activates N-methyl-D-aspartate (NMDA) receptors and increases the ux of calcium ions into the neurons,70 whereas calcium at toxic levels can kill the cells.71 Pretreatment of primary neuronal cells with HA reduced glutamate- and OPinduced toxicity and decreased neuronal death.61 The consequence of excitatory amino-acid-induced overstimulation has been implicated in a variety of acute and

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CREATE FUNCTION FunctionName (InputParameters) RETURNS Table AS RETURN (Select Statement);

To highlight just a few examples of regulations and their retention periods, Figure 9.3 shows four regulations. Each of those regulations has corresponding requirements as to how long data must be kept. Failure to meet these requirements can result in hefty nes or potential lawsuits. This mad scramble around compliancy should include a search for tools that help business become compliant. Remember, the tools can help business become compliant, but simply installing one tool or another will not make the business compliant. Tools available are just that tools for compliancy. Proper implementation of the tools and enforcement of the policies and rules can help a business or organization become compliant.

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In the preceding example, even is printed if the modulo of the division of num by 2 is 0; otherwise, odd is printed. The elif Statement While making decisions, you may want to include a condition in the else statement so that the statements in the else block are executed only when that condition is true. The elif statement in Python allows you to test multiple expressions for one truth value and executes a particular block of code as soon as one of the conditions evaluates to true. The syntax for an elif construct is this:

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In this equation is the dummy variable of integration. The value of the integral and H[s(t)] become in nite when t = and the integral is called improper for this reason. First, the problem of the exploding integral must be corrected. This is done by separating the integral into two or more integrals that avoid t = . H[s(t)] = (t) = h(t) s(t) s = lim 0 1

In order to understand the nature of get_xx functions, let s examine the working of the <get_businessDetail> function call. The following code shows the <get_businessDetail> XML message that is sent within the request SOAP message to the UDDI registry. This function call suggests that the UDDI registry return the registered details for business corresponding to the key 23453aef-af35-6a3f-c34abf798dab965a .

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