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Figure P9-1 A three-phase transmission line connecting two infinite busses together (a) If the per-phase (line-to-neutral) voltage on the sending infinite bus is 80 10 kV and the per-phase voltage on the receiving infinite bus is 76 0 kV, how much real and reactive power are being supplied by the transmission line to the receiving bus (b) If the per-phase voltage on the sending infinite bus is changed to 82 10 kV, how much real and reactive power are being supplied by the transmission line to the receiving bus Which changed more, the real or the reactive power supplied to the load



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B Hyperandrogenism (with Low or Normal FSH)

Excess testosterone may be secreted by adrenal tumors or by adrenal hyperplasia caused by steroidogenic enzyme defects such as P450c21 deficiency (salt-wasting) or P450c11 deficiency (hypertension) Ovarian tumors or polycystic ovaries may also secrete excess testosterone Androgenic steroids may also cause this syndrome

The initial endocrine evaluation should include serum determinations of FSH, LH, PRL, testosterone, TSH, FT4, and hCG (pregnancy test) Patients who are virilized or hypertensive require serum electrolyte determinations and further hormonal evaluation Girls with low-normal FSH and LH especially those with high PRL levels are evaluated by MRI of the hypothalamus and pituitary Girls who have a normal

C Ovarian Causes (with High FSH)

Figure 10-25





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Gonadal dysgenesis (Turner s syndrome and variants; see below) is a frequent cause of primary amenorrhea Ovarian failure due to autoimmunity is a common cause Rare deficiencies in certain ovarian steroidogenic enzymes are causes of

are normal have noncyclic secretion of gonadotropins resulting in anovulation Such women typically recover spontaneously but should have regular evaluations and a progestin withdrawal test about every 3 months to detect loss of estrogen effect PRL elevation due to any cause (see section on hyperprolactinemia) may cause amenorrhea Pituitary tumors or other lesions may cause hypopituitarism Corticosteroid excess of any cause suppresses gonadotropins

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(c) If the per-phase voltage on the sending infinite bus is changed to 80 15 kV, how much real and reactive power are being supplied by the transmission line to the receiving bus Compared to the conditions in part (a), which changed more, the real or the reactive power supplied to the load (d) From the above results, how could real power flow be controlled in a transmission line How could reactive power flow be controlled in a transmission line SOLUTION (a) If the shunt admittance of the transmission line is ignored, the relationship between the voltages and currents on this transmission line is

uterus and high FSH without the classic features of Turner s syndrome may require a karyotype to diagnose X chromosome mosaicism

Treatment of primary amenorrhea is directed at the underlying cause Girls with permanent hypogonadism are treated with estrogen replacement therapy (see below)

Torstveit MK et al Participation in leanness sports but not training volume is associated with menstrual dysfunction: a national survey of 1276 elite athletes and controls Br J Sports Med 2005 Mar;39(3):141 7 [PMID: 15728691] Warren MP et al The genetics, diagnosis and treatment of amenorrhea Minerva Ginecol 2004 Oct;56(5):437 55 [PMID: 15531861]

C Hyperandrogenism (with Low-Normal FSH)

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Elevated serum levels of testosterone can cause hirsutism, virilization, and amenorrhea In PCOS, GnRH pulses are persistently rapid, favoring LH synthesis with excessive androgen secretion; reduced FSH secretion impairs follicular maturation Progesterone administration can slow the GnRH pulses, thus favoring FSH secretion that induces follicular maturation Rare causes include adrenal P450c21 deficiency, ovarian or adrenal malignancies, ectopic ACTH secretion by a malignancy, and Cushing s disease Anabolic steroids also cause amenorrhea

Group A -hemolytic streptococci are not normal skin flora Streptococcal skin infections result from colonization of nor-

VS = VR + RI + jXI where I S = I R = I Therefore we can calculate the current in the transmission line as V VR I= S R + jX 80,000 10 76,000 0 I= = 265 05 A 103 + j525

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