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Cluster headache gets its name from its tendency to occur repetitively, once or twice each day, for several weeks, with long intervals of a year or more until it recurs in the same way. During the cluster, the attacks themselves are brief, lasting between 30 and 120 minutes. They often occur at the same time in each 24-hour cycle, with a predilection for the early hours of the morning. Functional brain imaging studies have shown activation of the brain s clock and central pain-sensitive areas at the onset of the attack. Cluster headache is much less common than migraine, and mainly affects men. The pain is excruciatingly severe, located around one eye, and accompanied by ipsilateral signs of autonomic dysfunction including redness and swelling, nasal congestion, or Horner s syndrome. The pain can sometimes be controlled by inhaling high- ow oxygen or injecting sumatriptan. Prophylactic treatment can be enormously helpful, starting with steroids and verapamil and moving on to methysergide or anticonvulsants (such as topiramate) if necessary.



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smaller file sizes (1/3 the size of an RGB background). This reduced file size is a huge bonus in terms of display speed; it s better for on-screen presentations, Web pages, and for printing. And finally, neutrals are least likely to be negatively affected by proprietary quirks and the vicissitudes of various display environments.

1 We use the term intuitive background in the same way as it is used in the rightly praised book on probability theory by [Feller 1968], who carefully distinguishes three aspects of a theory: the formal logical content, the intuitive background, and the applications.

Figure 7.1 Modelling both incoming services at the network edge and loads of service quality support bearers in the network core





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The other big problem facing insurance companies is called moral hazard. Moral hazard arises because buying insurance tends to change people s behaviour. For example, if you don t have car insurance, you re likely to drive much more slowly, knowing that you have to use your own money to pay for any damage you cause. But because you do have insurance, you may drive faster and more recklessly knowing that if something goes wrong, the insurance company is going to be stuck with the bill. Similarly, because you have contents insurance, you may be more prone to leaving your door unlocked. (Please know that when we say you in examples like this one, we don t actually mean you. We re quite sure that you re above moral hazard even if your friends and neighbours aren t.) Car insurance companies deal with moral hazard by offering discounts in exchange for high excesses. For example, if you get into an accident, the 1,000 excess that you ve chosen means that you have to pay the first 1,000 of any bills resulting from the accident.

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CPU time in the destination DINA node Clearly, as we add more CPU intensive applications (ie, increasing the load), the amount of resources available to the benchmark application reduces, and hence the amount of time required to nish the task increases The almost linear increase indicates that the overhead of managing many applications at the same node is relatively small However, at some point, around 30 CPU intensive applications, the system becomes unstable and the required time for termination increases sharply This point indicates that the load had reached its critical point, and increasing the load above this point may cause undesired behavior such as timeouts and the inability to perform all services Recall from 7 that in order to address scalability and load issues, the design of the DINA system allows several JVMs to be deployed on the same DINA node Figure 8.

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7 shows the completion time of our benchmark application when ve JVMs where present in the DINA node In such a case the CPU intensive load applications are shared among all JVMs almost equally; thus, the JVM in which the benchmark application is executed has only one fth of the load it would have if only one JVM was used However, the overall CPU usage is almost the same since we have ve JVMs each having about one fth of the load and one can see that the critical point appears at about the same load Note that the system becomes much more stable when the number of JVMs increases and the variant of the execution time becomes much smaller when we move from one JVM to ve JVMs and then to Ten JVMs in Figure 88.

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