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(Greg and Dan continue through NASDAQ Report, then Telco line transfer back to Dave Dyer) Dan: OK let s get back to, well, let s see, there s somebody calling in, but Dave Dyer is on the other line Dave, you were going to give me a little more info about what you think, uh, because Frank Cappiello said that in the end he liked the New York Times You have another newspaper you like better Dave: Right Yeah, you know, one of the things again, my theory is that if you just read whatever everybody else reads then you re probably not likely to have a big edge So I try to read some foreign material, and in particular as far as newspapers go, I like the Toronto Globe and Mail.



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Mass spectrometry is a technique with origins in the physical sciences that has fast become one of the most powerful techniques available for probing biological systems. Advances in mass spectrometry made possible by the advent of soft ionisation techniques have made possible detailed investigations into the primary structures of biological macromolecules and amphiphilic lipids. Indeed, mass spectrometry could be seen as the pre-eminent technique for determining the primary structures of polypeptides, nucleic acids, and complex carbohydrates owing to the possibility of obtaining molecular mass and sequence information using minute quantities of material (femtomole picomole, even attomole levels). Such information can be obtained without even the need for recombinant technologies (see 3). Hence, although three-dimensional information is not directly available by mass spectrometry, impressive amounts of primary structural information are nevertheless available that can be integrated with other pieces of information to try and provide useful insights into biological macromolecular structure without the need for analyses of the type presented in s 5 and 6. However, nowadays, mass spectrometry is also known to be essentially indispensable to the eld of proteomics, de ned as the study of all the interactions and implied functions of all the proteins expressed from a genome. Chemical biology and multidisciplinary thinking have very much driven the development of proteomics from the development of suitable mass spectrometric methods for large scale protein identi cation, to the development of suitable chromatographic systems to map out protein networks (Figure 9.1). In other words, mass spectrometry not only gives us primary structures but also has the capacity to de ne complex, functional, three-dimensional networks of interacting proteins and polypeptides within cells. Mass spectrometry quite simply lifts us from the opportunity to make detailed investigations into the structures and functions of certain biological macromolecules of interest





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Canadian newspapers in general are very, very good, and you can read stories without the political overtones that you get from American press So the Toronto Globe and Mail, which is available on the Internet for free, it s a great thing to read The other thing that I watch sometimes is the Canadian news on TV Now, we can t get Canadian TV here, and it s not part of any of the cable packages There s some sort of a copyright issue, but you can watch the podcasts And Canadian TV has a show called The National on CBC with a fellow named Peter Mansbridge, he s anchored that for ages He s sort of like a Walter Cronkite It s an hour-long news prog Dan: All right Dave, I guess we lost some time doing the market reports.

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Unless you assign a color to text on your Web page, the browser uses its own default, typically black. To change the font color for the entire page, choose Modify Page Properties and select a new color from the Text Color swatch. If your Preferences are set to use CSS, the style is written into an internal style sheet for body, td, and th selectors; otherwise, the color attribute is added to the <body> tag. You can also apply color to individual headings, words, or paragraphs that you have selected in Dreamweaver. As with text size, when working with CSS the best way to set a color for a selected tag or text range is to apply an existing style that includes the desired color. Font color is defined through the Type category of the CSS Rule Definition dialog or the color attribute of the Tag inspector s Relevant CSS category. Whether working in CSS or <font> tags, text color is expressed in either a hexadecimal color number or a color name. The hexadecimal color number is based on the color s red-green-blue value and is written like this:

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