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Tutorial Notes of the International Conference on Microelectronic Test Structure (ICMTS), Sweden, February 1999 18 Voldman S Electrostatic discharge protection, scaling, and ion implantation in advanced semiconductor technologies Invited Talk, Proceedings of the Ion Implantation Conference (I2CON), Napa, California, 1999 19 Richier C, Salome P, Mabboux G, Zaza I, Juge A, Mortini P Investigations on different ESD protection strategies devoted to 33 V RF applications (2 GHz) in a 0l8-mm CMOS process Proceedings of the Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium, 2000 p 251 59 20 Worley E, Bakulin A Optimization of input protection for high speed applications Proceedings of the Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium, 2002 p 62 73 21 Worley E, Matloubin M Diode with variable width metal stripes for improved protection against electrostatic discharge (ESD) current failure US Patent 6,518,604 (February 11, 2003) 22 Voldman C.



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adhesion, and virulence, which are secreted from the bacterial cytoplasm (Smith et al. 2000; Parisien et al. 2008; Vollmer et al. 2008), and endolysins, bacteriophage-encoded enzymes that reach and subsequently cleave the peptidoglycan, through membrane lesions formed by holins. This process results in lysis of the bacterial cell and the release of mature viral particles (Loessner et al. 1997; Navarre et al. 1999; Smith et al. 2000; Wang et al. 2000; Parisien et al. 2008; also see s 4 8). Endolysins have a modular structure and include domains responsible for amidase, peptidase, and N-acetylglucosaminidase activities. In addition they posses a cell wall-speci c targeting domain that is commonly found at the C-terminal end (Loessner et al. 1999; Navarre et al. 1999; Fig. 3.1). An interesting characteristic of some of these enzymes is that they induce cell lysis when added to the appropriate bacterial cells from the outside (Loessner et al. 1997; Loef er et al. 2001; Nelson et al. 2001; Schuch et al. 2002). B. anthracis belongs to the Bacillus cereus group of bacteria, which comprises closely related Firmicute organisms with highly divergent virulence properties (Hoffmaster et al. 2004). It was shown that the B. anthracis phage -encoded endolysin was capable of degrading peptidoglycan when applied externally to B. anthracis or to the closely related B. cereus strain RSVF1, resulting in a rapid lysis of the cell (Schuch et al. 2002). Furthermore, several other endolysins have been shown to induce cell lysis when added to the appropriate cells from the outside. Different endolysins were found to have different degrees of speci city. The group B streptococcal B30 bacteriophage endolysin is





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The effect of deep trench isolation, trench isolation, and sub-collector doping concentration on the ESD robustness of RF ESD diode structures in a BiCMOS SiGe technology Proceedings of the Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium, 2003 p 214 23 23 Baker L, Currence R, Law S, Le M, Lin ST, Teene M A waf e layout technique strengthens the ESD hardness of the NMOS output transistor Proceedings of the Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium, 1989 p 175 81 24 Beigel DF, Wolfe EL, Krieger WA Integrated circuit with diode-connected transistor for reducing ESD damage US Patent 5,637,901 (June 10, 1997) 25 Ker MD, Wu TS, Wang KF N-sided polygonal cell layout for multiple cell transistor US Patent 5,852,315 (December 22, 1998) 26 Voldman S ESD robustness and scaling implications of aluminum and copper interconnects in advanced semiconductor technology Proceedings of the Electrical Overstress/Electrostatic Discharge (EOS/ESD) Symposium, 1997 p.

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fact, time is your only money-making resource, and there s a sharply limited inventory about 40 to 60 hours per week per employee in your firm. So you can t afford to give your time away too cheaply. On the other hand, charge too much and you may price yourself out of the market, losing out on jobs to other business managers who charge less. In a slow economy or when business is down, we fear that customers and prospects won t buy from us because our prices are too high and we may be right. According to a Netscape Watercooler Poll (December 4, 2001), the two biggest signs of trouble are cancelled orders and delayed payments. If you ve experienced either, it may be cause for concern. The purposes of this chapter are to (1) help you determine exactly how much you can charge for your time and services and still remain competitive in your marketplace; (2) show you how to present your fees to potential customers over the phone, in a sales meeting, or in writing; (3) give you the confidence and tools you need to negotiate successfully and get the projects you want at the price you asked for; and (4) help you determine whether you should adjust your fees in a recession or economic slowdown or keep them firm.

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