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The bile acid binding resins include cholestyramine, colesevelam, and colestipol Treatment with these agents reduces the



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also had lower HDL cholesterol levels and high triglyceride levels In a VA study, gemfibrozil was also shown to reduce cardiovascular events in men with existing CHD whose primary lipid abnormality was a low HDL cholesterol There was no effect on all-cause mortality The fibrates are peroxisome proliferative-activated receptor-alpha (PPAR-alpha) agonists that result in potent reductions of plasma triglycerides and increases in HDL cholesterol They reduce LDL levels by about 10 15%, although the result is quite variable, and triglyceride levels by about 40% and raise HDL levels by about 15 20% The usual dose of gemfibrozil is 600 mg once or twice a day Side effects include cholelithiasis, hepatitis, and myositis The incidence of the latter two conditions may be higher among patients also taking other lipidlowering agents In the largest clinical trial that used clofibrate, there were significantly more deaths especially due to cancer in the treatment group; it should not be used





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Print iframe content - jQuery Forum
I am trying to create a print function that would print the content that is within the iframe . The iframe consists of locally hosted PDFs , website ...

incidence of coronary events in middle-aged men by about 20%, with no significant effect on total mortality The resins work by binding bile acids in the intestine The resultant reduction in the enterohepatic circulation causes the liver to increase its production of bile acids, using hepatic cholesterol to do so Thus, hepatic LDL receptor activity increases, with a decline in plasma LDL levels The triglyceride level tends to increase slightly in some patients treated with bile acid binding resins; they should be used with caution in those with elevated triglycerides and probably not at all in patients who have triglyceride levels above 500 mg/dL The clinician can anticipate a reduction of 15 25% in the LDL cholesterol level, with insignificant effects on the HDL level The usual dose of cholestyramine is 12 36 g of resin per day in divided doses with meals, mixed in water or, more palatably, juice Doses of colestipol are 20% higher (each packet contains 5 g of resin) The dose of colesevelam is 625 mg, 6 7 tablets per day These agents often cause gastrointestinal symptoms, such as constipation and gas They may interfere with the absorption of fat-soluble vitamins (thereby complicating the management of patients receiving warfarin) and may bind other drugs in the intestine Concurrent use of psyllium may ameliorate the gastrointestinal side effects

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Ezetimibe is a lipid-lowering drug that inhibits the intestinal absorption of dietary and biliary cholesterol by blocking passage across the intestinal wall by inhibiting a cholesterol transporter Ezetimibe reduces LDL cholesterol between 15% and 20% when used as monotherapy and can further reduce LDL in patients taking statins who are not yet at therapeutic goal The effects of ezetimide on CHD and its long-term safety are not yet known The usual dose of ezetimibe is 10 mg/d orally

C Hydroxymethylglutaryl-Coenzyme A (HMG-CoA) Reductase Inhibitors (Statins)

1163 - 115 100% = 11% 115

The HMG-CoA reductase inhibitors include atorvastatin, fluvastatin, lovastatin, pravastatin, rosuvastatin, and simvastatin These agents work by inhibiting the rate-limiting enzyme in the formation of cholesterol They reduce myocardial infarctions and total mortality in secondary prevention, as well as in older middle-aged men free of CHD A meta-analysis has demonstrated significant reduction in risk of stroke Cholesterol synthesis in the liver is reduced, with a compensatory increase in hepatic LDL receptors (presumably so that the liver can take more of the cholesterol that it needs from the blood) and a reduction in the circulating LDL cholesterol level by up to 35% There are also modest increases in HDL levels and decreases in triglyceride levels Oral doses are as follows: atorvastatin, 10 80 mg/d; fluvastatin, 20 40 mg/d; lovastatin, 10 80 mg/d; pravastatin, 10 40 mg/d; rosuvastatin, 5 40 mg/d; and simvastatin, 5 40 mg/d These agents are usually given once a day in the evening (most cholesterol synthesis takes place overnight); at the high end of the dose ranges, twice-a-day dosing may be used Side effects include myositis, whose incidence may be higher in patients concurrently taking fibrates or niacin Manufacturers recommend monitoring liver and muscle enzymes Several agents (notably erythromycin, cyclosporine, and azole antifungals) reduce the metabolism of these agents

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Print .js - Javascript library for HTML elements, PDF and image files ...
Print .js is a tiny javascript library to help printing from the web. ... Print .js was primarily written to help us print PDF files directly within our apps, without leaving the interface, ..... Callback function executed once the browser print dialog is closed.

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Silent printing in IE using PDF .JS - Experts Exchange
5 Mar 2019 ... Silent printing using pdf .js Hello I have simple page that prints pdf using pdf .js ... I' m getting javascript error when trying to upload the file












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