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Support modification ( editing ) of existing documents. Work in all ... There are other good open source JavaScript PDF libraries available. However, most of them ...

Vargas-Zepeda J et al Successful treatment of Naegleria fowleri meningoencephalitis by using intravenous amphotericin B, fluconazole and rifampicin Arch Med Res 2005 Jan Feb; 36(1):83 6 [PMID: 15900627]

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Acanthamoeba species and B mandrillaris can cause an encephalitis that is more chronic in nature than primary amebic meningoencephalitis Neurologic disease may be preceded by skin lesions, including ulcers and nodules After an uncertain incubation period neurologic symptoms develop slowly, with headache, meningismus, nausea, vomiting, lethargy, and low-grade fevers progressing over weeks to months to focal neurologic findings, mental status abnormalities, and eventually coma and death CT and MRI show single or multiple nonspecific lesions Lumbar puncture is dangerous due to increased intracranial pressure CSF shows a lymphocytic pleocytosis with elevated protein; amebas are not typically seen Diagnosis can be made by biopsy of skin or brain lesions Information on the treatment of granulomatous amebic encephalitis is limited Some patients have been successfully treated with various combinations of flucytosine, pentamidine, fluconazole or itraconazole, sulfadiazine, trimethoprim-sulfamethoxazole, and azithromycin

COCCIDIOSIS (CRYPTOSPORIDIOSIS, ISOSPORIASIS, CYCLOSPORIASIS, SARCOCYSTOSIS) & MICROSPORIDIOSIS General Considerations

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The causes of coccidiosis are Cryptosporidium species (C parvum, C hominis, and others); Isospora belli; Cyclospora cayetanensis; and Sarcocystis species Microsporidiosis is caused by at least 14 species, most commonly Enterocytozoon bieneusi and Encephalitozoon intestinalis These infections occur worldwide, particularly in the tropics and in regions where hygiene is poor They are causes of endemic childhood gastroenteritis (particularly in malnourished children in developing countries); institutional and community outbreaks of diarrhea; traveler s diarrhea; and acute and chronic diarrhea in immunosuppressed patients, in particular those with AIDS They are all notable for the potential to cause prolonged diarrhea, often lasting for a number of weeks Clustering occurs in households, day care centers, and among sexual partners The infectious agents are oocysts (coccidiosis) or spores (microsporidiosis) transmitted from person to person or by contaminated drinking or swimming water or food Ingested oocysts release sporozoites that invade and multiply in enterocytes, primarily in the small bowel Coccidian oocysts and microsporidian cysts can remain viable in the environment for years I belli and C cayetanensis appear to infect only humans C cayetanensis has caused a number of food-borne outbreaks in the United States in recent years, most commonly associated with imported fresh produce Sarcocystis infects many species; humans are intermediate hosts (infected by ingestion of fecal sporocysts) for some species but definitive hosts for Sarcocystis bovihominis and Sarcocystis suihominis (infected by ingestion of tissue cysts in undercooked beef and pork, respectively) Cryptosporidiosis is a zoonosis (C parvum principally infects cattle), but most human infections are acquired from humans, in particular with C hominus Cryptosporidia are highly infectious and readily transmitted in day care settings and households They have caused large community outbreaks due to contaminated water supplies (causing ~400,000 illnesses in Milwaukee in 1993) and are the leading cause of recreational water associated outbreaks of gastroenteritis Of note, coccidia and microsporidians will generally be missed on routine evaluations of stool for ova and parasites, as they require special staining techniques for identification.

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Edit *existing* PDF in a browser - Stack Overflow
Quick answer - no and it is quite unlikely you will find a cross-browser solution. It is very unlikely that you will find a PDF -perfect solution.

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Acanthamoeba keratitis is a painful, sight-threatening corneal infection It is associated with corneal trauma, most commonly after use of contact lenses and contaminated saline solution Symptoms include severe eye pain, photophobia, tearing, and blurred vision The keratitis progresses slowly, with waxing and waning clinical findings over months, and can progress to blindness Lack of response to antibacterial, antifungal, and antiviral topical treatments and potential use of contaminated contact lens solution are suggestive of the diagnosis Ocular examination shows corneal ring infiltrates, but these can also be caused by other pathogens The diagnosis can be made by examination or culture of corneal scrapings Available diagnostic techniques include examination of a wet preparation for cysts and motile trophozoites, examination of stained specimens, evaluation with immunofluorescent reagents, culture of organisms, and PCR Acanthamoeba keratitis can be cured with local therapy Topical propamidine isethionate (01%), chlorhexidine digluconate (002%), polyhexamethylene biguanide, neomycin-polymyxin B-gramicidin, miconazole, and combinations of these agents have been used successfully Oral itraconazole or ketoconazole can be added for deep keratitis Drug resistance has been reported Use of corticosteroid therapy is controversial In some cases, debridement and penetrating keratoplasty have been performed in addition to medical therapy Corneal grafting can be done after the amebic infection has been eradicated

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editing a pdf file using javascript : how to do? | Adobe Community ...
just realized that it is possible to edit PDF files using javascript . I have some, very small, experience in the past writing controls in javascript but.












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