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HIGH-ENERGY X-RAY FLUORESCENCE of this sample using the L lines, as can be seen in Figure 5.5.9(b). In addition, without such light elements, possibly 14 rare earth elements (from La to Lu except for Pm) and 42 peaks (L , L 1 , and L 2 lines for each element if we neglect the L line) are present in the XRF spectrum within the small energy region of 5.288 keV (=9.938 4.650). In contrast, in the energy region above 20 keV, there are no peaks other than the K lines of the heavy elements. Moreover, the energy difference between La K 1 (33.4418 keV) and LuK 1 (52.3889 keV) is ca. 19 keV, which is large enough to distinguish each rare earth element under the resolution of a pure Ge SSD, as is demonstrated in Figure 5.5.9(a). Certi ed values for the rare earth elements have not been reported for SRM612 glass, but information values (in ppm) are given as follows: Ag(21), Ba(41), La(36), Ce(39), Nd(36), Sm(39), Eu(36), Gd(39), Dy(35), Er(39), and Yb(42). The intensity of the peak of each element in Figure 5.5.9(a) appears to be qualitatively consistent with these information values. This suggests that the present technique is applicable for the nondestructive total determination of rare earth elements as well as for other heavy elements, such as Hf and Ta, at the ppm level.19



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The Smart Fasteners tab controls Smart Fasteners, which I discuss later in this chapter. The tab is shown in Figure 17.23. As an example of the types of settings you can use here, you can control which screw types are used with which types of Hole Wizard or non-Hole Wizard holes.

The while loop allows you to iterate through a block of code multiple times until a defined condition is met. The format of the while loop is:





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Finally, approximately 3% to 4% of individuals with Down syndrome have cells containing 46 chromosomes but still have the features associated with the syndrome due to translocation With translocation trisomy 21, genetic material from one chromosome 21 gets stuck or translocated onto another chromosome, either prior to or at conception Individuals with translocation to chromosome 21 have two normal chromosome 21s but also have additional chromosome 21 material on the translocated chromosome This translocation results in some of the indicators of Down syndrome but not all (Dreux et al, 2008) Diagnostic procedures are available for prenatal diagnosis of Down syndrome and are recommended by physicians usually based on maternal age or family history These include chorionic villus sampling (CVS), amniocentesis and percutaneous umbilical blood sampling (PUBS) These procedures involve a small risk of miscarriage, but are about 98% to 99% accurate in the detection of Down syndrome.

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unmanageable That s why corporate nancial statements are consolidated from the statements of divisions, subdivisions, and smaller and smaller organizational units Yet until very recently this could not be easily done with simulations: Their results could not be added up I will explain this property of simulations more precisely in later chapters, but for now let s return to the ladder analogy Consider a rm that has two divisions, each facing its own uncertainties We will model each division as its own ladder, and model the entire rm as the two ladders joined by a wooden plank Now suppose that by shaking either ladder by itself you would predict a 10 percent chance of its falling over A reasonable estimate of the chance of both ladders falling over at once is 10 percent times 10 percent, or 1 percent.

But when the two ladders are connected by the plank, all bets are off Now if either ladder falls, the plank may drag the other ladder down with it Thus, the chance of both falling at once goes from 1 percent to more like 20 percent! To simulate the entire enterprise, you can t simply shake each ladder individually and add up the results Instead you need to assemble both ladders and the plank rst, then shake the whole thing, as shown in Figure 31 But, again, as with the single gargantuan nancial statement spreadsheet, this just isn t practical for a large organization, let alone for a whole industry.

Figure 34.5 Ampli er input and output versus time. Agilent Technologies # 2008. Used with permission.

In The Failure of Risk Management: Why It s Broken and How to Fix It (Wiley, 2009), Doug Hubbard notes this problem as follows: [T]he lack of collaboration within rms makes another important step of risk management 5 almost impossible a cooperative initiative to build models of industrial, economics and global risks across organizational boundaries..

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Amniocentesis usually is performed between 15 and 22 weeks of gestation, CVS between 9 and 14 weeks, and PUBS after 18 weeks Risk factors for Down syndrome include advanced maternal age, parental balanced translocation, parents with chromosomal disorders, and a previous child with Down syndrome or other chromosomal disorder (M A Davidson, 2008) Because the risk of Down syndrome increases with mother s age, testing is encouraged in women over age 35 There is no evidence of toxins, drugs, vitamin de ciencies, or viruses that increase the risk of Down syndrome (M A Davidson, 2008)..

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