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Consider the simple semantic object model shown in Figure 5-26. A CUSTOMER object has one or more Addresses, one or more CONTACTs, and one or more ORDERs. The CONTACT class contains only simple attributes. The ORDER class contains a simple Date and a group attribute to hold information about Items ordered. This model leads immediately to three relational tables: Customers, Contacts, and Orders.



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future use. The second edition is for full CAD PACS integration requiring elaborate collaboration between the CAD developer and the PACS manufacturer. The third edition does not require the elaborate integration efforts of the two parties, and proper use of the CAD-PACS toolkit is suf cient, which favors the independent CAD developer. 26.3.4 Functions of the Three Editions

8

Figure 8.4 The multi-frequency network in Figure 8.2 reduced to a frequency-converting twoport network

where 01 are the L singular values of the matrix A H ,and [glhi . . . c ~ ~ h i ] = HDiU, where U is the left singular vectors of A H . Since both Di and U

Binding Atomic energy mass (MeV) (umu)





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Numerous studies have established rm links between obesity and diabetes. Particularly clear associations have emerged from circumscribed ethnic groups with high susceptibility to diabetes. A classic example is the Pima Indians of Arizona, whose adult prevalence rates of obesity and diabetes are respectively 60 and 40%. In a 23-year longitudinal study of over 3000 Pima Indians, preceding obesity was strongly associated with increased incidence of diabetes, even in subjects with no family history of the disease (Knowler et al., 1991). Unselected populations also show strong associations. The much-cited study of Colditz et al. (1995) reported that the risk of men developing diabetes over a 14-year period rose steeply as BMI increased above a surprisingly low value of 25 kg/m2. The risk for those aged 40 49 years whose BMI was 35 kg/m2 was almost 80 times higher than in those with a BMI of 22 kg/m2, while those aged 50 59 had a 40-fold increased risk at BMI 35 kg/m2

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Either way, digital outputs are preferable to speaker channel outputs from your PC (these are sometimes called direct attachments, or direct speaker attachments). These appear in 4 in Figures 4-2 and 4-4, and use various colors (such as lime green, black, and orange) to label speaker channels to which they correspond. RCA mini-jacks are the most common type of connectors for such outputs, which link up to similar inputs on speaker rigs (but not to the various receivers and pre-amplifiers we surveyed for this book). Better PC speaker rigs including those we reviewed for this book support both optical and coaxial digital audio inputs as well (and that s what we used for our auditioning, mostly because it was much easier to hook up one cable instead of three or more).

By replacing eq. (1.79) into eq. (1.13), the equation system (1.77) is rewritten as Ig,0 (V ) = 0 0 C 0 C V1i V1r + +

(12.30)

Figure 6 6 Contours of the Poisson log-likelihood function. (Example 6.8) ..

indeed, Lemieux et al. (2000) have suggested that high cardiovascular risk can be identi ed simply by a waist circumference that exceeds 90 cm in men (or 85 cm in women) and triglyceride concentration of 2.0 mmol/l. Plasma lipid screening may also reveal other relevant abnormalities, such as familial hyperlipidaemia or dyslipidaemia due to alcohol excess or hypothyroidism. Liver function tests, especially transaminase levels. The most common cause of moderately elevated transaminase levels in obese subjects is hepatic steatosis, but it must be remembered that these may be normal, even in some cases with advanced in ammation and brosis. TSH and free thyroxine levels. These should be measured if hypothyroidism is suspected, with a lower threshold of suspicion in middleaged and older women. ECG. This may show signs of ischaemia or previous myocardial infarction, but is relatively insensitive for the latter. In obese subjects, the ECG may be falsely suggestive of inferior myocardial ischaemia or even ischaemia (see 12).

At this stage, the overall fold of the polypeptide chain and secondary structure features such as alpha-helices and beta-sheet are clearly de ned. The nal step in the procedure is re nement of the structure to a resolution of a few A. This will often involve the use of statistical information obtained from high-resolution databases of structures derived from crystallographic measurements as well as more sophisticated analysis of NMR data. More information on protein structure re nement is given below in Section 6.5.8.

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