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, 259, 1 15 151 Schulman, S, Gitel, S, and Martinowitz, U (1994), Stability of factor VIII concentrates after reconstitution, Am J Hematol, 45, 217 223 152 Osterberg, T, Fatouros, A, Neidhardt, E, Warne, N, and Mikaelsson, M (2001), B-domain-deleted recombinant factor VIII formulation and stability, Semin Hematol, 38, 40 43 153 Andrade, J D, and Hlady, V (1986), Protein adsorption and materials biocompatibility: A tutorial review and suggested hypothesis, Adv Polym Sci, 79, 1 63 154 Duncan, M R, Lee, J M, and Warchol, M P (1995), In uence of surfactants upon protein/peptide adsorption to glass and polypropylene, Int J Pharm, 120, 179 188 155 Wang, P L, Udeani, G O and Johnston, T P (1995), Inhibition of granulocyte colony stimulating factor (c-csf) adsorption to polyvinyl chloride using a nonionic surfactant, Int J Pharm.



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, 114, 177 184 156 Burke, C J, Steadman, B L, Volkin, D B, Tsai, P K, Bruner, M W, and Middaugh, C R (1992), The adsorption of proteins to pharmaceutical container surfaces, Int J Pharm, 86, 89 93 157 Weber, S S, Wood, W A, and Jackson, E A (1977), Availability of insulin from parenteral nutrient solutions, Am J Hosp Pharm, 34, 353 357 158 Weeren, R V, and Gibboni, D J, Barrier packaging as an integral part of drug delivery, available: http://wwwdrugdeliverytechcom/cgi-bin/articles=52 (accessed June 1, 2007) 159 U S Patent 5,028,431: Franz, T J, Shah, K R, and Kydonieus, A Article for the Delivery to Animal Tissue of a Pharmacological Active July 2, 1991; U Patent 5,242,433: Smith, J A, and Murphy, B.

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, Packaging System with In-Tandem Applicator Pads for Topical Drug Delivery Decemeber 7, 1992 160 U S Patent 5,698,217: Wilking, S L Transdermal Drug Delivery Device Containing a Dessicant December 16, 1997 161 Hoye, W L, Mogalian, E M, and Myrdal, P B (2005), The effects of extreme temperatures on drug delivery of albuterol sulfate hydro uoroalkane inhalation products, Am J Health-Syst Pharm, 62(21), 2271 2277 162 European Pharmacopoeia (EP) (2001), Preparations for inhalation, EP supplement 2001: 2918, EP, Strasbourg, France 163 US Food and Drug Administration (FDA) (1998), Guidance for industry: Metered dose inhaler (MDI) and dry powder inhaler (DPI) drug products, FDA CDER, Washington, DC 164 Petersson, G, and Wiren, J E (1980), The brochodilator response from inhaled terbutaline is in uenced by the mass of small particles: A study on a dry powder inhaler (Turbuhaler), Eur Respir 2, 253 256..

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