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Some researchers evaluated the role of living arrangements (alone, married, marital disruption), while others focused on instrumental support such as access to community services and activities It was shown that a small social network confers a two- to threefold increase in the likelihood of developing CAD over time It is also imperative to look at the qualitative nature of social support (ie, amount of perceived emotional support) Low levels of perceived emotional support were shown to confer greater than a threefold increase in the risk of future cardiac events (Blazer, 1982) Furthermore, Berkman, Leo-Summers, and Horwitz (1992) showed a threefold increase in future cardiac events in post-MI patients who reported low levels of emotional support, while R Williams et al (1992) observed a threefold increase in mortality over a ve-year period among CAD patients who were unmarried or had no major con dant in their life.



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Altman, G.H., Diaz, F., Jakuba, C., Calabro, T., Horan, R.L., Chen, J., Lu, H., Richmond, J., Kaplan, D.L. (2003) Silk-based biomaterials. Biomaterials 24: 401 416. Altman, G.H., Horan, R.L., Lu, H.H., Moreau, J., Martin, I., Richmond, J.C., Kaplan, D.L. (2002a) Silk matrix for tissue engineered anterior cruciate ligaments. Biomaterials 23: 4131 4141. Altman, G.H., Horan, R.L., Martin, I., Farhadi, J., Stark, P.R., Volloch, V., Richmond, J.C., Vunjak-Novakovic, G., Kaplan, D.L. (2002b) Cell differentiation by mechanical stress. FASEB J. 16: 270 272. Amiel, D., Frank, C., Harwood, F., Fronek, J., Akeson, W. (1984) Tendons and ligaments: a morphological and biochemical comparison. J. Orthop. Res. 1: 257 265. Bramono, D.S., Richmond, J.C., Weitzel, P.P., Kaplan DL, Altman GH. (2004) Matrix metalloproteinases and their clinical applications in orthopaedics. Clin Orthop Relat Res. 2004 Nov;(428): 272 85. Chen, E.H., Black, J. (1980) Materials design analysis of the prosthetic anterior cruciate ligament. J. Biomed. Mater. Res. 14: 567 586. Chen, J., Altman, G.H., Karageorgiou, V., Horan, R., Collette, A., Volloch, V., Colabro, T., Kaplan, D.L. (2003) Human bone marrow stromal cell and ligament broblast responses on RGD-modi ed silk bers. J. Biomed. Mater. Res. 67A: 559 570. Chiquet, M. (1999) Regulation of extracellular matrix gene expression by mechanical stress. Matrix Biol. 18: 417 426.





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treated pork muscle and control. Thus, aside from the obvious increase in tenderness, HDS treatment as a tool to decrease microbial loads and prolong the shelf life of meat products remains undetermined, and additional research is needed to support this concept.

Other evidence also supports the positive association between social factors and the development of CAD Cultural and familial support are critical aspects on one s overall.

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Long-term liabilities are those due more than one year after the balance sheet date. Included in this category would be mortgages, bonds, debentures, and notes payable. If there are any long-term loans from stockholders, they also would appear in that section.

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This includes three cycles: heating, temperature holding, and cooling. Time-temperature relationships during the heating phase are calculated according to microbial destruction and enzyme inactivation criteria, as described earlier, whereas cooling is applied for practical reasons, such as handling. Commercial sterilization can be carried out by several methods, all based on the theoretical principles already discussed. The main methods are batch still retorts or continuous operations. The batch method is still used in large industrial operations handling cans and glass jars, and all types of containers in small operations. However, Crang and others (2006) describe a process for bottling and canning sausage meat with domestic equipment. The authors concluded that some of the products in jars of thicker glass require a longer processing time to give the same level of safety. The method basically consists of loading the retort, closing it, and lling it with steam. The second cycle, temperature holding, depends on the time-temperature relationship to satisfy the processing parameters (D, z, F). Cooling is carried out by closing the steam valves and injecting cold water into the retorts. Care must be taken to gradually reduce the retort pressure in order to avoid deformation or breaking of containers. Continuous retorts are generally used in large operations. The retort pressure difference is controlled to avoid deformation of

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An annual operating period may be any 12-month period beginning on any date and ending on any date 12 months later. In addition, a business entity may use an interim reporting period such as weekly, monthly, quarterly, or semiannually.

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