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Propagation mode (1) is concerned with the attenuation of signals subject to tropospheric propagation via near-great-circle paths. Determination of coordination distance for this case is covered in 3 of RR Appendix S7. There is a choice between two methods. The numerical method is intended principally for use with the aid of a computer. It is covered in detail in 3.2.2 of RR Appendix S7. The alternative graphical method given in 3.2.3 of this appendix is equally valid and all necessary graphs are given in the appendix. By either method, the starting point is the value of minimum permissible basic transmission loss for a given percentage of the time and the coordination distance is derived taking into account the radioclimatic zone or zones traversed, the frequency, percentage of time and horizon angle from the earth station.



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2:6-1

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In these bands, there is a need for the provision of services on a competitive basis between GSO FSS and non-GSO FSS as well as between non-GSO FSS and non-GSO FSS. Further studies are required on sharing conditions. WRC-97 Resolution 130 requests ITU-R to conduct them in time for consideration by WRC-2000.

No. of Stream(s)

Labeled packet MAC header PPP header Shim header Shim header Network header Network header Labeled packet Labeled packet encoding





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Qinghaosu can be used by physicians for the treatment for chloroquine-resistant malaria; it must have a different mode of action from that of chloroquine Early study by Chinese scientists demonstrated that artemisinin drugs had a direct parasiticidal action against P falciparum in the erythrocytic stage both in vitro and in vivo274 Also, the morphologic changes were observed under the electron microscope274 Qinghaosu drugs were added to the media, and samples were taken at de nite intervals for electromicroscopic examination The injuries of membrane structures of the parasite included swelling of the limiting membrane and the nuclear membrane, and, formation of the autophagic vacuole It was also found that some free radical scavengers, such as vitamin E, would reduce the ef ciency of qinghaosu However, the inherent reason for these observed phenomena have not been acknowledged 56.

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13 This is why although, at rst sight, screening for breast cancer seems like a good idea, the whole issue has become very controversial.

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3 The Free Radical Reaction of Qinghaosu and Its Derivatives With Fe(II) Qinghaosu is a sesquiterpene molecule containing carbon, hydrogen, oxygen, and no nitrogen atoms and can used by physicians for the treatment of multidrugresistant strains of P falciparum It is obvious that its antimalarial mechanism is different from previous alkaloidal antimalarial drugs such as quinine and chloroquine Since the discovery of 1, what will be its action mode on the molecular level is a widely interesting question, although it is a dif cult task Actually until now, the action mode of quinine and other synthetic alkaloidal antimalarial drugs has not been so clearly understood275 Qinghaosu acts parasite at its intra-erythrocytic asexual stage At this stage, the parasite takes hemoglobin as its nutritional resource, digests hemoglobin, and leaves free heme, which is then polymerized to parasite safety poly-heme (hemozoin).

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