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Using Walk and Fly modes can result in some jerkiness as you make little adjustments along the way. For a smoother ride, you can draw a motion path and save a movie file that automatically runs along the path. You need to specify both the camera and its target. They can be either a point or a path (line, arc, elliptical arc, ellipse, circle, polyline, 3D polyline, or spline), but they can t both be a point. For example: If the camera is a point and the target is a circle, the resulting movie is like standing in one place and turning around. If the camera is a circle and the target is a point, the result is like walking around a point (such as the center of a table) that you look at throughout. The first step is to create one or two motion paths for the camera and/or the target. If you are using paths, a polyline is ideal if you want to add some turns, because you can only select one object.



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The endocannabinoid system, although discovered only relatively recently, has already produced one drug that has reached clinical practice, with several others in development. The appetite-stimulating properties of cannabis have been recognized for many years but were unexplained until the cloning of the CB1 and CB2 cannabinoid receptors that recognize tetrahydrocannabinol, the active ingredient. Further work led to the discovery of the endocannabinoids, endogenous lipid neurotransmitters that are also agonists at cannabinoid receptors; they stimulate feeding via the CB1 receptor, and are now known to be involved in the physiological regulation of energy balance (Gerard et al., 1991; Shire et al., 1996). Endocannabinoids are synthesized on demand within neurones from arachidonic acid, and include anandamide and 2-arachidonoglycerol (2-AG) (Kirkham, 2005). The endocannabinoid CB1 system has been implicated in mediating the effects of leptin on food intake, and also in the hedonic aspects of eating (Higgs, Williams and Kirkham, 2003; Di Marzo et al., 2001). Animals with genetic and dietary obesity show increased endocannabinoid activity (as evidenced by





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that sharpen institutional priorities and ensure a strategic approach to the organization s future. In other words, effective boards both oversee strategic planning procedures (Type I) and work with management to determine what matters most to the long-term future of the organization (Type II). The position we take here represents a shift in emphasis.We share the view expressed by Hamel and Prahalad (1997) that formal planning processes are too often strategy as form filling. . . . turning the crank on the planning process once a year . . . [going] through the motions of an annual planning cycle . . . [producing] weighty strategic plans that adorn executive book cases, all without any clue as to whether a company has a truly unique and stretching point of view about the future. In short, process becomes ritual, with the board largely on the sidelines. Strategic planning exercises rarely drill to the core questions of institutional identity, outmoded assumptions, and breakthrough strategies. Unless and until ideas, rather than plans, are the drive motors of strategy, the full range of trustees talents will be vastly underutilized.As strategies are hatched and plans unfold, boards, along with CEOs, should be more akin to architects than general contractors or, worse, tradesmen. In order to fulfill this role boards must work in a strategic, not fiduciary, mode.

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Figure 6-55: After an article has been defined and the OK button is clicked, the Article Properties dialog box opens.

distributed packet switching [194] R.M. Metcalfe and D.R. Boggs. Ethernet: computer networks. Communications of the ACM, 19(7):395-404, 1976. [195] J.F. M ey er. Computation-based ers, 25(6):578-584, 1976. [196] J.F. Meyer. IEEE On evaluating reliability analysis. IEEE Transactions

is widely distributed in the brain (Turnley et al., 1999), whereas mTOR appears to be mainly con ned to NPY/AgRP neurones in the ARC (Cota et al., 2006). The responsiveness of AMPK and mTOR to hormones as well as metabolites (Figure 6.8) suggests a broad role in integrating information about fuel availability and endocrine status. These two fuel-sensitive kinases therefore appear to have reciprocal functions, and the balance between them may re ect overall energy availability. An emerging concept is that changes in AMPK and mTOR sensing in the brain in response to fuel surplus inhibit eating, and vice versa.

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