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PDFescape is the first online PDF reader, editor , form filler, and form creator ... PDFescape is entirely web based, relying on XHTML, JavaScript , XML, and AJAX . mates are about 100,000 cases and 48,000 deaths, mostly due to T b gambiense, leading to the loss of 15 million disabilityadjusted life years Infections are rare among travelers, including visitors to game parks Exposure to tsetse flies, with subsequent bite lesion Irregular fever, headache, joint pain, rash, edema, lymphadenopathy progressing to somnolence, and neurologic abnormalities Trypanosomes in blood or lymph node aspirates; positive serologic tests Trypanosomes and increased white cells and protein in cerebrospinal fluid jspdf edit existing pdf editing a pdf file using javascript : how to do? | Adobe Community ...
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Acrobat JavaScript Editor and Debugger Console . . . . .19 ..... You can enhance an Adobe Portable Document Format ( PDF ) document so that it contains fields to ... 1 West African trypanosomiasis Chancres at the site of the bite are uncommon After an asymptomatic period that may last for months, hemolymphatic disease presents with fever, headache, myalgias, arthralgias, weight loss, and lymphadenopathy, with discrete, nontender, rubbery nodes, referred to as Winterbottom s sign when in a posterior cervical distribution Other common signs are mild splenomegaly, transient edema, and a pruritic erythematous rash Febrile episodes may be broken by afebrile periods of up to several weeks The hemolymphatic stage progresses over months to meningoencephalitic disease, with somnolence, irritability, personality changes, severe headache, and parkinsonian symptoms progressing to coma and death 2 East African trypanosomiasis Chancres are more commonly recognized with T b rhodesiense infection, with a painful lesion of 3 10 cm and regional lymphadenopathy that appears about 48 hours after the tsetse fly bite and lasts 2 4 weeks East African disease follows a much more acute course, with the onset of symptoms usually within a few days of the insect bite The hemolymphatic stage includes intermittent fever and rash, but lymphadenopathy is less common than with West African disease Myocarditis can cause tachycardia and death due to arrhythmias or heart failure If East African trypanosomiasis is left untreated, it progresses over weeks to months to meningoencephalitic disease, somnolence, coma, and death African trypanosomiasis is caused by the hemoflagellates Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense The organisms are transmitted by bites of tsetse flies (genus Glossina), which inhabit shaded areas along streams and rivers Trypanosomes ingested in a blood meal develop over 18 35 days in the fly; when the fly feeds again on a mammalian host, the infective stage is injected Human disease occurs in rural areas of sub-Saharan Africa from south of the Sahara to about 15 degrees south latitude T b gambiense causes West African trypanosomiasis, and is transmitted in the moist sub-Saharan savannas and forests of west and central Africa T b rhodesiense causes East African trypanosomiasis, and is transmitted in the savannas of east and southeast Africa T b rhodesiense infection is primarily a zoonosis of game animals and cattle; humans are infected sporadically Humans are the principal mammalian host for T b gambiense, but domestic animals can be infected African trypanosomiasis is an increasing threat, especially where control has been disrupted by civil strife The largest number of cases is in the Democratic Republic of the Congo Annual incidence esti- Definitive diagnosis requires identification of trypanosomes Microscopic examination of fluid expressed from a chancre or lymph node may show motile trypanosomes or, in fixed specimens, parasites stained with Giemsa During the hemolymphatic stage, detection of parasites in Giemsa-stained blood smears is common in East African disease but difficult in West pdf editor javascript How to add text to an existing PDF file using JavaScript on a website ...
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