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A close-up of this interface is shown in Figure 1453(b) Because of refraction, the test beam is incident on the part at a large angle For a 417 angle of incidence and an index of 15, the angle of incidence at the test surface is 86 This is close to the critical angle of the prism There are two bene cial consequences to this con guration First, the sensitivity of the test is reduced by the cosine of the angle of incidence At 86 , the sensitivity is 7% of the normal incidence sensitivity; a fringe represents 7 waves of surface height change instead of a half wave It is as if the surface is tested with a longer wavelength.



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It can be seen from figure 6.11 that when using MRC the traffic bearer could only be maintained when RxLev was high and calls were frequently dropped when the interfering signal was present. Further, the quality of the call was generally poor from both measurements and the subjective quality reported by the field trial team. Array control based on GOB (see figure 6.12) was able to maintain a bearer for a longer period when compared to the MRC results. However, there is still a large link outage and the subjective quality of the link was poor. The optimum combining approach, as given in figure 6.13, was able to maintain the link for the full duration of the trial. Here, the average link quality was below that expected for GSM (3.2), however an acceptable subjective quality audio report was recorded until the wanted mobile station and interferer were coincident within the azimuth plane of the array. Figure 6.14 shows the bearer quality recorded for the spatial reference beamforming approach using the combination of MUSIC and a Kalman filter in order to determine the parameters of the beamformer. It can be seen that initially the call quality is good, but as the wanted mobile approaches the interferer the call quality falls and tracking becomes unreliable (see figure 6.10), with a considerable link outage. Finally, figure 6.15 shows the





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drug product dosage form and all established speci cations for the attributes being considered. When the stability data for all three batches on stability at various sampling intervals show little variability from initiation of the stability study, the drug product can be considered stable and no statistical analysis of the data is required. Where the data show change in quantitative attributes (API and degradation amounts, dissolution rates), the time at which the 95% one-sided con dence limit for the mean curve intersects the acceptance criteria should be de ned. When the analysis shows small batch-to-batch variation, combining the data into an overall estimate is recommended by applying appropriate statistical tests to the slopes of regression lines and zero-time intercepts for the individual batches. The overall shelf life should be based on the minimum time during the stability study a drug product can be expected to remain within acceptance criteria. Appropriate statistical methods should be considered to test the goodness of t of the data on all batches and where applicable combined batches to the assumed degradation line or curve [7]. The stability evaluation should cover the levels of degradation products and other appropriate attributes. The mass balance, that is, whether the addition of assay value and degradation products add up to 100% of the initial value, should be considered taking into account the margin of analytical error of the method used. Details on stability evaluation are discussed in Section 7.1.7. 7.1.5.6 Stability Commitment

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The second bene t is that almost everything, including a ground surface, is highly re ective at this angle of incidence, and a variety of different materials and samples can be used If the angle of the light in the prism is slightly changed, the optical path length in the air gap will change much more than the path in the glass This tilt when used produces the phase shift between the reference and test beams Systems are available with up to a 200 mm aperture, and have been applied to testing silicon wavers and machined or ground parts The clear drawback to a system such as this is the need for the large precision glass prism.

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