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multi-institutional trials. A morphology index (MI) score of 5 or more is 89% sensitive and 70% speci c for ovarian cancer. The mean MI for malignant ovarian tumors is 7.3 and for benign lesions is 3.3. However, the positive predictive value is 46%, meaning that half of the masses with a score of 5 or greater are actually benign.9 Other imaging methods such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) have a limited role in evaluating an adnexal mass, as they rarely provide additional useful information over an ultrasound (Table 8.2). However, one or more of these modalities may be indicated in certain situations. A CT scan of the abdomen and pelvis is often obtained preoperatively to search for distant metastases when ultrasound or clinical examination is highly suspicious for malignancy. A chest CT is usually added when the chest X-ray is abnormal. CT ndings that are highly suspicious for malignancy include ascites, omental caking, lymphadenopathy, peritoneal thickening or implants, hepatic or lung metastases, and ureteral obstruction. MRI is useful in distinguishing adnexal from uterine pathology, and assessing the size, consistency, and location of leiomyomas. PET scan is not an appropriate modality for initial evaluation of a pelvic mass, but can have an important role in clinical management once a malignancy has been diagnosed.2



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Common to all solutions related to the layer 1 network control plane is the need to accommodate the dynamic aspects of Grid applications. These applications frequently have one or more of the following requirements:

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leading to the value of its invariant as I1 = 1/16 2 . When normalized appropriately, this then provides a measure of ellipticity 16 2 I if I 1 , 1 1 16 2 EI = 1 otherwise, 16 2 I1 which ranges over [0, 1], peaking at 1 for a perfect ellipse. The same approach was applied to triangles, all of which have the value I1 = 1/108, and the triangularity measure is 108I if I 1 , 1 1 108 TI = . 1 otherwise. 108I1 Of course, using a single moment invariant is not very speci c, and so the above two measures will sometimes incorrectly assign high ellipticity or triangularity values to some other nonelliptical or triangular shapes. This can be remedied using more moment values, either in the above framework, or as described next. Voss and S e describe a method for tting geometric primitives by the method of u moments [63]. The data are normalized into a (if possible unique) canonical frame, which is generally de ned as the simplest instance of each primitive type, by applying an af ne transformation. Applying the inverse transformation to the primitive produces the tted primitive. For example, for an ellipse they take the unit circle as the canonical form, and the circle in the canonical frame is transformed back to an ellipse, thereby providing an ellipse t to the data. For the purposes of generating shape measures, the inverse transformation is not necessary as the measures can be calculated in the canonical frame. This is done by computing the differences between the normalized moments of the data (mij ) and the moments of the canonical primitive (mij ) where only the moments not used to determine the normalization are included: 1 +

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understand why they are seen as inadequate (Cleaver and Freeman 1995) A number have grown up in care themselves and do not want this for their children Others may have mild to moderate learning dif culties or mental health problems A small number are self-absorbed and either preoccupied in their own need or see the child as a means for their own grati cation The children, whatever the family dif culties, are usually very frightened, may be psychologically frozen and paralysed or may become depressed or angry and de ant Once in care, they may blossom physically but many may miss their parents and be distressed and preoccupied, or for a period they may switch off and become detached Many of these children have diagnosable psychopathology as well as poor physical health (McCann et al, 1996).

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