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A HTML5 client-side solution for generating PDFs. Perfect for event tickets, reports, certificates, you name it! While many cases can be successfully treated medically, operative management is frequently required Acute heart failure unresponsive to medical therapy is an indication for valve replacement even if active infection is present, especially for aortic valve infection Infections unresponsive to appropriate antimicrobial therapy after 7 10 days (ie, persistent fevers, positive blood cultures despite therapy) are more likely to be eradicated if the valve is replaced Surgery is nearly always required for cure of fungal endocarditis and is more often necessary with gram-negative bacilli It is also indicated when the infection involves the sinus of Valsalva or produces septal abscesses Recurrent infection with the same organism prompts an operative approach, especially with infected prosthetic valves Continuing embolization presents a difficult problem when the infection is otherwise responding; surgery may be the proper approach Particularly challenging is a large and fragile vegetation demonstrated by echo in the absence of embolization Most clinicians favor an operative approach, vegetectomy with valve repair if the patient is a good candidate Embolization after bacteriologic cure does not necessarily imply recurrence of endocarditis pdf xchange editor javascript console PDFKit
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