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Frostbite is injury due to freezing and formation of ice crystals within tissues In mild cases, only the skin and subcutaneous tissues are involved; the symptoms are numbness, prickling, and itching With increasing severity, deep frostbite involves deeper structures, and there may be paresthesia and stiffness Thawing causes tenderness and burning pain The skin is white or yellow, loses its elasticity, and becomes immobile Edema, blisters, necrosis, and gangrene may appear MRI with magnetic resonance angiography and triple-phase bone scanning have been used to assess the degree of involvement in severe frostbite and to distinguish viable from nonviable tissue



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Exposure of the extremities to cold produces immediate localized vasoconstriction followed by generalized vasoconstriction When the skin temperature falls to 25 C, tissue metabolism is slowed, but the demand for oxygen is greater than the slowed circulation can supply, and the area becomes cyanotic At 15 C, tissue metabolism is markedly decreased and the dissociation of oxyhemoglobin is reduced; this gives a deceptive pink, well-oxygenated appearance to the skin Tissue damage occurs at this temperature Tissue death may be caused by ischemia and thromboses in the smaller vessels or by actual freezing Freezing (frostbite) does not occur until the skin temperature drops to 4 to 10 C or even lower, depending on such factors as wind, mobility, venous stasis, malnutrition, and occlusive arterial disease Neuropathic sequelae such as pain, numbness, tingling, hyperhidrosis, cold sensitivity of the extremities, and nerve conduction abnormalities may persist for many years after the cold injury





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Evaluate and treat the patient for associated systemic hypothermia 1 Rewarming Superficial frostbite (frostnip) of extremities in the field can be treated by firm steady pressure with the warm hand (without rubbing), by placing fingers in the armpits, and, in the case of the toes or heels, by removing footwear, drying feet, rewarming, and covering with adequate dry socks or other protective footwear For deep frostbite, rapid thawing at temperatures slightly above body heat may significantly decrease tissue necrosis If there is any possibility of refreezing, the frostbitten part should not be thawed, even if this might mean prolonged walking on frozen feet Refreezing results in increased tissue necrosis Rewarming is best accomplished by immersing the frozen extremity for several minutes in a moving water bath heated to 40 42 C until the distal tip of the part being thawed flushes Water in this temperature range feels warm but not hot to the normal hand Dry heat (eg, stove or open fire) is more difficult to regulate and is not recommended After

Z 1 = 25 3687

NOTE See 17, Protecting Your Network, for an in-depth look at firewalls and other security options

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Keep warm, keep moving, and keep dry Individuals should wear warm, dry clothing, preferably several layers, with a windproof outer garment Wet clothing, socks, and shoes should be replaced with dry ones Extra socks, mittens, and insoles should always be carried in a pack in cold or icy areas Cramped positions, constricting clothing, and prolonged dependency of the feet are to be avoided Arms, legs, fingers, and toes should be exercised to maintain circulation Wet and muddy ground and exposure to wind should be avoided

Affected parts are elevated to aid in removal of edema fluid, and pressure sites (eg, heels) are protected with pillows Later treatment is as for Buerger s disease (see 12)

Aslam AF et al Hypothermia: evaluation, electrocardiographic manifestations, and management Am J Med 2006 Apr;119 (4):297 301 [PMID: 16564768] Di Lorenzo G et al Is there a role for antileukotrienes in urticaria Clin Exp Dermatol 2006 May;31(3):327 34 [PMID: 16681569] Kempainen RR et al The evaluation and management of accidental hypothermia Respir Care 2004 Feb;49(2):192 205 [PMID: 14744270] McCullough L et al Diagnosis and treatment of hypothermia Am Fam Physician 2004 Dec 15;70(12):2325 32 [PMID: 15617296] Smith LO Alpine climbing: injuries and illness Phys Med Rehabil Clin N Am 2006 Aug;17(3):633 44 [PMID: 16952756] Ulrich AS et al Hypothermia and localized cold injuries Emerg Med Clin North Am 2004 May;22(2):281 98 [PMID: 15163568]

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