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Hybrid Strategy Helps to Precipitate up to a 60% Reduction in Safety Stock Situation: A large contract manufacturer of circuit boards and other hightech components sells high-value, short life-cycle products. Our manufacturing processes are very complex and include an involved sequence of assemblies at different stages, requiring us to hold large amounts of finished goods inventory, according to a production and inventory control manager. We long recognized that a make-to-stock philosophy was not the ideal strategy for our supply chain, she explained. Our goal was to streamline our supply chain to meet three specific objectives : reducing safety stock levels without sacrificing service levels, reducing promised lead time to customers while reducing inventory and increasing service performance, and developing a flexible supply selection process. We also wanted to examine these objectives under different cycle times, inventory turns, and safety stock assumptions, she offers. We selected Inventory Analyst, a multistage inventory optimization solution, to assist us in redesigning our supply chain to a hybrid strategy where portions of the supply chain are make-to-stock while others operate in a make-to-order environment, the P&IC manager offered. The solution helped us to pinpoint the appropriate supply chain push-pull boundary, determine the optimal location of inventory across the manufacturing process, and calculate the optimal quantity of safety stock for each component at each stage. The end result is a supply chain with a lower inventory holding cost, reduced inventory liability issues, increased customer service levels, and reduced customer lead times. Specifically, she cited the following achievements: Overall, we were able to reduce safety stock levels in the range of 40% to 60% for the same customer lead times, and also achieved over 30% reduction in safety stock for products where the committed lead time was reduced by 50%.



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The chapter concludes with presenting a collection of open problems that arise from both the network abstraction and the routing protocol itself.





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use the pathology report information to optimize patient therapy A brief discussion of important pathologic aspects for the most common vulvar in ammatory dermatoses follows The most common in ammatory disorder involving the vulva is eczematous dermatitis, which is characterized histologically by the presence of intercellular edema, spongiosis within the epidermis, and a variably intense dermal chronic in ammatory in ltrate There are several clinical variants of eczematous dermatitis based on clinical features of the condition; these variants usually cannot be subtyped on histology alone Once the pathologist has made the diagnosis of eczematous dermatitis and excluded other dermatoses, it is then up to the clinician to then search for the speci c etiology Eczematous dermatitis is the histopathologic counterpart to contact dermatitis in most patients, with the differential diagnosis including both irritant contact dermatitis and allergic contact dermatitis.

In general, postdiction studies of juror knowledge reveal that potential jurors often overestimate the accuracy of eyewitness identi cation; they are insensitive to the impact of crime seriousness on identi cation, fail to appreciate the problems of biased lineup instructions, and are insensitive to the issues that contribute to inaccuracy of cross-racial identi cations (Devenport et al, 1997)..

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Reduce Overhead Costs by Using a Less Paper-Intensive Human Resource System. Challenge: Action: Implement first phase of SAP human resource system. We selected and implemented this challenging program. Ultimately, this will lead to an integrated HR/benefits/payroll/training system that eliminates duplicate entry and massive paper movement. Now,

Common causes of irritant contact dermatitis include soaps, perfumes, cleansers, topical over-the-counter medications, urine, sweat, and friction Irritant contact dermatitis results from direct damage to the skin by exogenous agents Allergic contact dermatitis is rarer and may be more dif cult to con rm without skin patch testing Histopathologic features in skin biopsies favoring allergic contact dermatitis include the presence of increased eosinophils around super cial venules and occasionally within the spongiotic epidermal layer, and intraepidermal microgranulomas consisting of Langerhans cells Allergic contact dermatitis represents a type IV hypersensitivity reaction to a speci c allergen Fungal infections may occasionally show histopathologic features similar to eczematous dermatitis and should be excluded by the pathologist, especially given the different treatment implications The absence of fungal organisms in the biopsy can be con rmed with special stains such as the periodic acid Schiff (PAS) stain.

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