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Other changes are the result of political or economic activities Thus, the pressures on organizations are mounting, and organizations must be ready to take responsive actions if they are to succeed In addition, organizations may see opportunities in these pressures For a Framework for Change Analysis see Online File W14 at the book s Web site for 1 Organizational responses to the increasing business pressures are described next..

Reading, speaking and listening: these three forms of language processing have both similar and different properties. One similarity is that the meaning of

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A Raman spectrometer has to analyze weak Raman radiation at different wavelengths and the very strong 'Rayleigh radiation', i.e., 'unshifted' radiation at the wavelength of the exciting radiation. This is produced at or in the sample by Rayleigh scattering, reflection, or refraction at powder particles or the sample container. The Rayleigh line has a radiant power which may exceed that of the Raman lines by about lo6 up to 10". The necessary resolving power of a Raman spectrometer is higher than that of an infrared spectrometer. A line at A6 = 1000 cm in the Raman spectrum with a half width of 1 cm- observed in the visible spectrum near 500 nm (20000 cm-'), needs a resolving power of R = 20000. For a line at 3 = 1000 cm in the infrared with a half width of 1 cm I , R = 1000 is sufficient. The necessary resolving power can usually be made available by common prism and grating spectrometers or by interferometers. Raman spectra of gases require instruments with a resolving power R up to lo5... lo6. They are recorded with specially designed grating spectrometers (Brodersen, 1979; Weber, 1979) or interferometers (Jennings, Weber and Brault, 1986).





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where r is the ef ciency-corrected counting rate in a downstream detector. Another interesting and important use of radiotracers in industry is in wear and corrosion studies. In studies of wear (tribology) one labels the part under study with a radionuclide. The radioactivity is concentrated on the surface undergoing wear by plating, diffusion, or ion implantation with a low-energy accelerator. The labeled part is put in service and, typically, one measures the radioactivity released in the lubricant as a measure of wear. Calibrations of the technique can be done to get absolute measures of wear.

Multisheet names do not appear in the Name box or in the Go To dialog box (which appears when you select Edit Go To). In other words, Excel enables you to define the name, but it doesn t give you a way to automatically select the cells to which the name refers.

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161 Graves P R, Haystead T A J (2003) A functional proteomics approach to signal transduction Recent Prog Horm Res 58: 1 24 162 Ping P (2003) Identi cation of novel signaling complexes by functional proteomics Circ Res 93: 595 603 163 Godovac-Zimmermann J, Brown L R (2003) Proteomics approaches to elucidation of signal transduction pathways Curr Opin Mol Ther 5: 241 249 164 Cavanagh J, Benson L M, Thompson R, Naylor S (2003) In line desalting mass spectrometry for the study of noncovalent biological complexes Anal Chem 75: 2949 2954 165 Juraschek R, Dulcks T, Karas M (1999) Nanoelectrospray more than just a minimized- ow electrospray ionization source J Am Soc Mass Spectrom 10: 300 308 166 Chang D Y, Lee C C, Shiea J (2002) Detecting large biomolecules from highsalt solutions by fused-droplet electrospray ionization mass spectrometry Anal Chem.

74: 2465 2469 167 Minton A P (2001) The in uence of macromolecular crowding and macromolecular con nement on biochemical reactions in physiological media J Biol Chem 276: 10577 10580 168 Minton A P (2000) Implications of macromolecular crowding for protein assembly Curr Opin Struct Biol 10: 34 39 169 Davis-Searles P R, Saunders A J, Erie D A, Winzor D J, Pielak G J (2001) Interpreting the effects of small uncharged solutes on protein-folding equilibria Annu Rev Biophys Biomol Struct 30: 271 306 170 Hall D, Minton A P (2003) Macromolecular crowding: qualitative and semiquantitative successes, quantitative challenges Biochim Biophys Acta 1649: 127 139 171 Medalia O, Weber I, Frangakis A S, Nicastro D, Gerisch G, Baumeister W (2002) Macromolecular architecture in eukaryotic cells visualized by cryoelectron tomography Science 298: 1209 1213 172 Ellis R J (2001).

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