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(1997c) Beta 3-adrenergic-receptor allele distributions in children, adolescents and young adults with obesity, underweight or anorexia nervosa Int J Obes Relat Metab Disord, 21, 224 230 Hixson, JE, Almasy, L, Cole, S, Birnbaum, S, Mitchell, BD, Mahaney, MC, Stern, MP, MacCluer, JW, Blangero, J & Comuzzie, AG (1999) Normal variation in leptin levels is associated with polymorphisms in the proopiomelanocortin gene, POMC J Clin Endoc Metab, 84, 3187 91 Holder, JL, Butte, NF & Zinn, AR (2000) Profound obesity associated with a balanced translocation that disrupts the SIM1 gene Hum Molec Genet, 9, 101 108 Holland, AJ, Sicotte, N & Treasure, J (1988) Anorexia nervosa: Evidence for a genetic basis J Psychosom Res, 32, 561 571 Hsu, LKG, Chesler, BE.



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On a personal level, Engelbart s attitudes gradually matured from an interest in a steady job, getting married and living happily ever after, to a drive to contribute to society as expressed in his question: How can my career maximize my contribution to mankind 4 His study of Bush s Memex concept brought him to envision people using graphic displays that would represent an information space that could be explored and used to formulate and organize their ideas with incredible speed and exibility Realizing that he would need to expand his technology capabilities to accomplish the goal of maximizing his contribution to mankind, he enrolled in graduate school at the University of California at Berkeley to continue his studies in electrical engineering He received his PhD.





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& Santhouse, R (1990) Bulimia nervosa in eleven sets of twins: A clinical report Int J Eat Disord, 9, 275 282 Huszar, D, Lynch, CA, Fairchild-Huntress, V, Dunmore, JH, Fang, Q, Berkemeier, LR, Gu, W, Kesterson, RA, Boston, BA, Cone, RD, Smith, FJ, Camp eld, LA, Burn, P & Lee, F (1997) Targeted disruption of the melanocortin-4 receptor results in obesity in mice Cell, 88, 131 141 Inui, A (2000) Transgenic study of energy homeostasis equation: Implications and confounding in uences FASEB Jl, 14, 2158 2170 Jackson, RS, Creemers, JW, Ohagi, S, Raf n-Sanson, ML, Sanders, L, Montague, CT, Hutton, JC & O Rahilly, S.

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in 1955, and after a short period as an assistant professor at UC Berkeley, he accepted a position at the Stanford Research Institute (SRI) In 1962, Engelbart prepared a forward-thinking article entitled Augmenting Human Intellect: A Conceptual Framework 5 This paper was the product.

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(1997) Obesity and impaired prohormone processing associated with mutations in the prohormone convertase 1 gene Nat Genet, 16, 303 306 Jenkinson, CP, Cray, K, Walder, K, Herzog, H, Hanson, R & Ravussin, E (2000) Novel polymorphisms in the neuropeptide-Y Y5 receptor associated with obesity in Pima Indians Int J Obes Relat Metab Disord, 24, 580 584 Kapeller, R, Moriarty, A, Strauss, A, Stubdal, H, Theriault, K, Siebert, E, Chickering, T, Morgenstern, JP, Tartaglia, LA & Lillie, J (1999) Tyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signalling by insulin J Biol Chem, 274, 24980 24986 Karvonen, MK, Koulu, M, Pesonen, U et al.

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