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The final step is to add Y error bars to the chart, using the Y Error Bars tab of the Format Data Series dialog box. For this example, the Plus display option is used, along with a Custom + error amount. The values used for the custom error bars are in range D2:D11. For data points in which the predicted Y value is greater than the actual Y value, the error bar extends upward from the data point. For data points in which the predicted Y value is less than the actual Y value, the error bar extends downward from the data point. The sum of these deviations will always be 0.



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To install the firmware onto your camera, you will have to copy it to a CF (CompactFlash) card. The CF card you use has to be at least 8MB, but less than 2GB. When you have a CF card that meets this requirement, check to be sure it s blank. If not, copy any data you want to keep off the card. Once you are satisfied that there is nothing important on the card that you don t have a copy of somewhere else, format it. This eliminates any possibility that the card is corrupt.





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(the FDA associate director of medical policy who was at the Holiday Inn hearing on antidepressants) Temple urged him to transfer to the FDA, and Garvey spent five years at the agency, rising through three promotions to become supervising medical officer in the cardio-renal division, where he oversaw other doctors doing reviews on heart and kidney drugs During his tenure, Garvey said, he personally ran the main review on what would become the blockbuster Tagamet for heartburn and supervised the review for another big heartburn drug, Zantac He also continued working part-time at the NIH while keeping up a small private practice He left the FDA in 1981 for family reasons, and decided that he liked working from home so much that he never went back Today, like many former FDA reviewers, Garvey is a consultant to the industry he once regulated.

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It turns out that glamour models are very much like the rest of us. They may have minor blemishes on their skin that would distract from glamour photographs. Most lenses are made to resolve as much detail as possible, so the sharp lenses work against the photographer s desired effect in a glamour shot. In many instances, the blemishes can be hidden by make-up, as shown in Figure 14-8. In other instances, the glamour photographer will have to use a soft-focus lens or a soft-focus filter, otherwise known as a diffusion filter. A soft-focus lens or filter will obscure detail slightly, smooth out the blemishes, and, under the right lighting conditions, cover the model in an intriguing haze. It creates soft, pleasing portraits that are very attractive in glamour shots.

As president of his own firm in Potomac, Maryland, he helps write drug applications for biotech and pharmaceutical companies, including such big players as Merck & Co, GlaxoSmithKline, Lilly, and Genentech It can be done, Garvey said of reviewing an NDA You start reading You try to get over the panic, over the immensity of it all You read around You sit there late at night and go line by line (In the case of Garvey s first effort, Reglan was ultimately approved) Imagine what someone goes through to prepare for a presidential debate, to study for the bar exam, to defend a PhD thesis in an oral grilling, to proofread Proust s In Search of Lost Time, to work without sleep for four days in a row and then put that all together.

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That is a little bit what it is like to work on an application to sell a new drug in the United States On both sides for the company that is submitting the application, and the FDA division reviewing it the work is careful, intense, efficient, repetitive, scientific, arbitrary, and painstaking all at once There must be data documenting every change in the condition of every patient tested, and those data must be cross-referenced several places in the NDA Every decimal point must be accurate A lot of money is riding on the reviewer s decision So are a lot of lives More than anything else, this approval process is what defines the FDA It lies at the heart of the Type I versus Type II question and creates the most headlines.

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