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damage (known as reflux esophagitis), characterized by single or multiple erosions or ulcers in the distal esophagus at the squamocolumnar junction However, endoscopy is normal in up to 50% of symptomatic patients with gastroesophageal reflux, a condition sometimes referred to as nonerosive reflux disease The Los Angeles classification grades esophageal abnormalities on a scale of A (one or more isolated mucosal breaks 5 mm that do not extend between the tops of two mucosal folds) to D (one or more mucosal breaks that involve at least 75% of the esophageal circumference) Initial medical therapy for gastroesophageal reflux disease is guided by the presence of symptoms, not the endoscopic findings Hence, endoscopy is not warranted for most patients with typical symptoms suggesting uncomplicated reflux disease Endoscopy should be performed in patients whose symptoms have not responded after initial empiric therapy and patients with symptoms suggesting complicated disease (dysphagia, odynophagia, occult or overt bleeding, or iron deficiency anemia) 2 Barium esophagography This study plays a limited role In patients with severe dysphagia, it is sometimes obtained prior to endoscopy to identify a stricture 3 Ambulatory esophageal pH monitoring Ambulatory pH monitoring is the best study for documenting acid reflux, but it is unnecessary in most patients Dual-channel transnasal probes are sometimes used to measure reflux in the proximal esophagus or hypopharynx in patients with atypical reflux symptoms, especially laryngitis, cough, and asthma Esophageal pH monitoring is indicated in the following situations: (1) to document abnormal esophageal acid exposure in a patient being considered for antireflux surgery who has a normal endoscopy (ie, no evidence of reflux esophagitis); (2) to evaluate patients with a normal endoscopy who have reflux symptoms unresponsive to therapy with a proton pump inhibitor; (3) to detect either abnormal amounts of reflux or an association between reflux episodes and atypical symptoms such as noncardiac chest pain, asthma, chronic cough, laryngitis, and sore throat It is recommended that most patients with atypical symptoms first be given an empiric trial of antireflux therapy with a double-dose proton pump inhibitor for 2 3 months If symptoms fail to improve, a pH study is then performed.



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javascript ; October 20, 2013; By Sam Deering. Load PDF into iframe and call print . Code snippet to Load PDF into iframe and call print . Also see: 10 JQUERY  ...

My Traceroute (MTR) is a dynamic (keeps running) equivalent to TRACEROUTE MTR is not available on Windows Here s a sample of MTR output:

The subtransient motor current will be the same as the current flowing from Bus 4 to Bus 3 This current is given in per-unit above The actual motor current is found by multiplying by the base current in Region 3:





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The clinical manifestations of protein energy malnutrition range from mild growth retardation and weight loss to a number of distinct clinical syndromes Children in the developing world manifest marasmus and kwashiorkor In secondary protein energy malnutrition as seen in industrialized nations, clinical manifestations are affected by the degree of protein and energy deficiency, the underlying illness that resulted in the deficiency, and the patient s nutritional status prior to illness Progressive wasting that begins with weight loss and proceeds to more severe cachexia typically develops in most patients with marasmus-like secondary protein energy malnutrition In the most severe form of this disorder, most body fat stores disappear and muscle mass decreases, most noticeably in the temporalis and interosseus muscles Laboratory studies may be unremarkable serum albumin, for example, may be normal or slightly decreased, rarely decreasing to < 28 g/dL In contrast, owing to its rapidity of onset, kwashiorkorlike secondary protein energy malnutrition may develop in patients with normal subcutaneous fat and muscle mass or, if the patient is obese, in patients with excess fat and muscle The serum protein level, however, typically declines and the serum albumin is often < 28 g/dL Dependent edema, ascites, or anasarca may develop As with primary protein energy malnutrition, combinations of the marasmus-like and kwashiorkor-like syndromes can occur simultaneously, typically in patients with progressive chronic disease in whom a superimposed acute illness develops

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The treatment of severe protein energy malnutrition is a slow process requiring great care Initial efforts should be directed at correcting fluid and electrolyte abnormalities and infections Of particular concern are depletion of potassium, magnesium, and calcium and acid base abnormalities The second phase of treatment is directed at repletion of protein, energy, and micronutrients Treatment is started with modest quantities of protein and calories calculated according to the patient s actual body weight Adult patients are given 1 g of protein and 30 kcal/ kg Concomitant administration of vitamins and minerals is obligatory Either the enteral or parenteral route can be used, although the former is preferable Enteral fat and lactose are withheld initially Patients with less severe protein calorie undernutrition can be given calories and protein simultaneously with the correction of fluid and electrolyte abnormalities Similar quantities of protein and calories are recommended for initial treatment Patients treated for protein energy malnutrition require close follow-up In adults, both calories and protein are advanced as tolerated, adults to 15 g/kg/d of protein and 40 kcal/kg/d of calories Patients who are re-fed too rapidly may develop a number of untoward clinical sequelae During refeeding, circulating potassium, magnesium, phosphorus, and glucose move intracellularly and can result in low serum levels of each The administration of water and sodium with carbohydrate refeeding can overload hearts with depressed cardiac function and result in congestive heart failure Enteral refeeding can

Excess adipose tissue, resulting in BMI > 30 Upper body obesity (abdomen and flank) of greater health consequence than lower body obesity (buttocks and thighs) Associated with multiple metabolic and structural disorders, including diabetes mellitus, hypertension, and hyperlipidemia

Obesity is one of the most common disorders in medical practice and among the most frustrating and difficult to manage Little progress has been made in prevention or treatment, yet major changes have occurred in our understanding of its causes and its implications for health

Obesity is defined as an excess of adipose tissue Accurate quantification of body fat requires sophisticated techniques

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