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When high-voltage electrical injury occurs, extensive deep tissue necrosis should be suspected Deep tissue necrosis leads to profound tissue swelling Because deep tissue compartments in the arms and legs are contained by unyielding fascia, these compartments must be opened by surgical fasciotomy to prevent further soft tissue, vascular, and nerve death Electrical burn injuries remain the most devastating and underrecognized burn injuries, causing amputations (often because of unrecognized compartment syndromes) and acute renal failure, resulting in part from rhabdomyolysis Creatine kinase levels are usually elevated in patients with severe electrical burns (and constitute a negative prognostic indicator) Severe (often underrecognized) muscle necrosis due to electrical burns may occur in the absence of significant skin burns



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Burn patients require extensive support An attempt must be made to maintain normal core body temperature (by maintaining environmental temperature at or above 30 C) in patients with burns over more than 20% of total body surface area, since the hypermetabolic state of burns is exacerbated by subnormal temperatures Respiratory injury, sepsis, and multiorgan failure are common Enteral feedings may be started once the ileus of the resuscitation period has resolved, usually the day after the injury There is often a markedly increased metabolic rate after burn injury, due in large part to whole body synthesis and increased fatty acid substrate cycles If the patient does not tolerate low-residue tube feedings, total parenteral nutrition should be started without delay through a central venous catheter Contrary to conventional teachings, data indicate that most patients can be fed adequately with energy equal to 100% to 120% of estimated basal energy expenditure (BEE) A useful guide is to provide 25 kcal/kg body weight plus 40 kcal per percent of burn surface area Early aggressive enteral nutrition reduces infections, noninfectious complications, length of hospital stay, impaired healing, and mortality Anticatabolic treatments such as blockade, growth hormone, insulin, oxandrolone, and synthetic testosterone have been advocated Occasionally, acute respiratory distress syndrome or respiratory failure unresponsive to maximal ventilatory support may develop in burn patients In addition, the incidence of venous thromboembolism in the lower extremities is high among burn patients Duplex ultrasonography is the best method for identifying venous thromboembolism Early pulmonary dysfunction after severe burn injury is widely recognized It is now appar-





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In general, when burn wounds are seen in the emergency department, the causative agents have been eliminated However, acute burns caused by hydrofluoric acid should be treated by water rinsing followed by application of topical calcium Treatment of the burn wound is based on several principles (1) Protection from desiccation and further injury of those burned areas that will spontaneously reepithelialize in 7 10 days by application of topical antibiotic such as silver sulfadiazine or mafenide acetate Silver sulfadiazine is the most popular topical agent It is painless, easy to apply, and effective against most strains of Pseudomonas (2) Regular and thorough cleansing of burned areas is a critically important intervention in burn units Early excision and grafting of burned areas may be performed as soon as 24 hours after burn injury or when the patient will hemodynamically tolerate the excision and grafting procedure Systemic infection remains a leading cause of morbidity among patients with major burn injuries, with nearly all severely burned patients having one or more septicemic episodes during the hospital course Coagulase-negative staphylococci (63%) and Staphylococcus aureus (20%) are commonly cultured from burn wounds Methicillin-resistant S aureus and Pseudomonas aeruginosa are also commonly cultured but usually later in the hospital course Methicillin resistance in grampositive organisms is becoming common, but vancomycin-

ent in children that late and permanent pulmonary dysfunction with later obstructive and restrictive lung disease can result from major burn injury Ophthalmologic consultation is indicated early when ocular or corneal injury is suspected Prevention of long-term scars remains a formidable problem in seriously burned patients The V-beam laser (or longpulsed dye laser) is emerging as adjunctive treatment to the usual regimen of corticosteroid injections, silicone patches, compression, and scar revision Permanent sequelae can be avoided by prevention of infection, early aggressive rehabilitation, compressive garments, and early psychological support Facial transplantation has become a controversial but potential treatment for those patients with devastating unreconstructable facial burns Complex reconstructions of severely burned structures such as the neck, hand, and arm continue to benefit from improved plastic surgical microsurgical reconstructions

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